SERVICES / PRESBYOPIA

Presbyopia

Presbyopia affects virtually everyone over the age of 40–45 years. It is associated with a progressive decline in near vision and is caused by age-related changes in the eye’s crystalline lens, which gradually loses its ability to focus on nearby objects.

What is presbyopia?

Presbyopia affects virtually everyone over the age of 40–45 years. It is associated with a progressive decline in near vision and is caused by age-related changes in the eye’s crystalline lens, which gradually loses its ability to focus on nearby objects.

Although current technology cannot restore the eye’s natural accommodative function after the crystalline lens has been replaced with an intraocular lens, it offers a range of effective treatment options that can significantly improve near vision and reduce dependence on glasses. The most appropriate approach is tailored to each patient’s visual needs, lifestyle, and expectations.

Causes of Presbyopia

Presbyopia is primarily due to the natural ageing process of the crystalline lens, which gradually becomes stiffer and less elastic with age. At the same time, the ciliary muscle—the mechanism that helps the lens change shape—gradually becomes less effective. Genetic and environmental factors may also play a role, particularly in the onset and severity of symptoms. These include prolonged near work, extended screen use, and inadequate lighting.

Symptoms of Presbyopia

The primary symptom of presbyopia is blurred near vision. Initially, symptoms are often more noticeable in dim lighting or when performing prolonged near tasks, such as reading a map in the car at night. It often causes headache, eye strain, and a feeling of tired or heavy eyes. Many patients also report an improvement in other non-specific ocular symptoms, such as tearing and redness, after appropriate correction of their presbyopia.

Diagnosis of Presbyopia

Presbyopia is diagnosed through a comprehensive ophthalmic examination.
The specialist ophthalmologist evaluates:

An accurate diagnosis is essential for selecting the most appropriate treatment strategy for each patient.

Treatment of Presbyopia

Presbyopia is effectively treated with a range of treatment options, tailored to each patient’s age, visual needs, occupation, and lifestyle.

Presbyopia Glasses

These may include:

Contact Lenses

Specially designed contact lenses are also available for presbyopia, including multifocal contact lenses and monovision correction, in which one eye is corrected for distance vision and the other for near vision.

Refractive Laser Surgery

In selected cases, refractive surgery can significantly improve near vision, especially when presbyopia coexists with myopia, astigmatism, or hyperopia.

PRELEX — Refractive Lens Exchange & Premium Intraocular Lenses

Refractive Lens Exchange (RLE), widely known as PRELEX (PResbyopic Lens EXchange) or as Clear Lens Extraction (CLE) or Near-Clear Lens Extraction, is the procedure of choice for the permanent correction of presbyopia in patients approximately 50 years of age and older. The procedure is particularly indicated when early opacities of the crystalline lens are present or when patients wish to achieve simultaneous correction of coexisting refractive errors, such as myopia, hyperopia, or astigmatism.
Technically, the procedure is identical to modern cataract surgery. Through a 2.2-mm microincision, the natural crystalline lens is removed using phacoemulsification and replaced with a customized intraocular lens (IOL). The difference is that the lens is removed before it develops a visually significant cataract.
PRELEX provides a permanent solution for presbyopia while simultaneously correcting coexisting refractive errors. Because the natural crystalline lens is replaced with an artificial intraocular lens, cataracts cannot develop in the future.
Careful selection of the most appropriate premium intraocular lens is the key factor in achieving the best possible visual outcome.
At Athens Vision, we tailor the choice of intraocular lens from among the main categories of premium IOLs—enhanced monofocal, extended depth of focus (EDOF), trifocal, and toric—to maximize visual performance and reduce dependence on glasses, based on the anatomy of the eye, the patient’s visual needs, and lifestyle and personal expectations.
Medication — Eye Drops for Presbyopia
In recent years, a new class of eye drops has been developed to temporarily improve near vision in patients with mild to moderate presbyopia. Their mechanism of action is based on pharmacological miosis (pupil constriction), which increases the depth of focus through the pinhole effect, allowing clearer vision at near distances. The effect is temporary, usually lasting 6–10 hours, and therefore requires daily administration.
Since 2021, the U.S. Food and Drug Administration (FDA) has approved four eye drops for presbyopia: Vuity (pilocarpine 1.25%, AbbVie, 2021), Qlosi (pilocarpine 0.4%, Orasis Pharmaceuticals, 2023), Vizz (aceclidine 1.75%, LENZ Therapeutics, 2025)—which introduced a new pharmacological mechanism beyond pilocarpine—and, most recently, YUVEZZI (Tenpoint Therapeutics, 2026), the first combination eye drop approved for the same indication.
Currently, none of these eye drops are commercially available in the European Union, as they have not yet been approved by the European Medicines Agency (EMA). Consequently, pharmacological treatment for presbyopia is not currently available for patients in Greece or elsewhere in the European Union.
Since 2021, Athens Vision has been using a pilot galenic formulation in selected patients with presbyopia, particularly following refractive laser surgery for myopia or hyperopia, with encouraging clinical results.
Even in countries where they are available, these eye drops provide temporary symptomatic relief and are indicated primarily for younger patients with mild presbyopia. Known side effects include headache, reduced night vision due to pupil constriction, conjunctival hyperaemia, and—particularly with pilocarpine-based formulations—rare but documented retinal complications, including retinal tears and retinal detachment in predisposed eyes.
Athens Vision closely monitors developments in this field and will offer these treatments to appropriately selected patients as soon as they receive EMA approval.
The choice of treatment is always individualized to achieve the best possible functional visual outcome for each patient.

Prevention of Presbyopia

Although presbyopia cannot be prevented, early diagnosis and appropriate visual correction can help reduce visual discomfort and improve quality of life.
The following are recommended:

Laser Treatment for Presbyopia

At Athens Vision, we offer a range of laser vision correction procedures tailored to each patient’s individual visual needs and lifestyle.
Modern laser refractive surgery is a well-established, safe, and effective treatment option for appropriately selected patients.
In the third decade of the 21st century, refractive surgery has established itself as a permanent, safe, and cost-effective solution for nearly all refractive errors (myopia, astigmatism, hyperopia, and selected cases of presbyopia).
The millions of patients who have been freed from their glasses through laser surgery are tangible proof of the value of refractive surgery in treating myopia, astigmatism, hyperopia, and selected cases of presbyopia.

Read more here.

Frequently Asked Questions

We can help you decide whether correcting your myopia, astigmatism, hyperopia, or presbyopia is the best option for you.

In general:

  • You must be at least 18 years of age (an exception is made for procedures performed to gain admission to a military academy/ security forces/fire department/naval academies, etc. In such cases, the decision to perform the procedure is individualized, and social and professional factors are taken into account in the final decision to perform (or not) of an invasive procedure before reaching the age of legal majority, which requires parental consent)

  • to be in good overall health,

  • stable vision over the past year

  • You must not have any chronic conditions affecting the cornea, the retina, or other eye diseases

  • If you are a woman, this treatment is contraindicated during pregnancy and while breastfeeding.

Of course, to determine whether you are a suitable candidate for myopia correction, you will need to undergo a comprehensive preoperative evaluation, which includes a series of tests:

  • Full History

  • Complete Refractive Examination

  • Goldmann Tonometry

  • Comprehensive Fundus Examination (Optic Nerve, Macula, Periphery)

  • Refraction (Visual Acuity Test)

  • Automated Keratometry

  • Ammeter

  • Examination Under a Slit Lamp

  • Measurement of the Mesoptic Diameter of the Pupil

  • Eye Movement

  • Circular Refraction

  • Tear Film Measurement (Schirmer Test)

  • Corneal Topography

  • Topography of the Anterior and Posterior Corneal Surfaces – Scheimpflug

  • Pachymetry

  • Measurement of Ocular Inertia & IOP with the Ocular Response Analyzer (Assessment of the mechanical properties of the cornea)

Presbyopia and hyperopia are both refractive errors that cause blurred near vision. However, they have different underlying causes. Presbyopia occurs when the eye’s lens loses its elasticity. Hyperopia occurs when the eyeball is too short or the cornea is too flat.

Yes, and it’s very common. Myopia means that your eyes naturally focus too much, resulting in clear near vision but blurry distance vision. However, if you’re nearsighted and over 40, you’ll still experience symptoms of presbyopia even when wearing your glasses or contact lenses. Your eye doctor can adjust your lens prescription to correct both presbyopia and nearsightedness.

Doctors who specialize in this condition

ANASTASIOS CHARONIS

Ph.D. from the University of Freiburg, Board Certified by the American and European Boards of Ophthalmology
Specialties: Corneal Surgery – Transplants, Cataracts, Refractive Surgery, Pediatric Ophthalmology, Strabismus

Gerasimos Kopsinis

Director of the Glaucoma Department at AthensVision, PhD from the University of Athens
Specialties: Glaucoma, Cataracts

Theodoros Filippopoulos

Scientific Director of Athens Vision, Board Certified by the American Board of Ophthalmology
Specialties: Glaucoma Surgery, Cataract Surgery

Maria Zozolou

Graduate of the Medical School of the University of Athens, PhD from the Medical School of the University of Athens, Board Certified by the European Board of Ophthalmology
Specialties: Refractive Surgery, Cataracts

Georgia Kosti

Board Certified by the European Board of Ophthalmology, Clinical Fellow of the “G. P. Georgariou” Scholarship
Specialties: Refractive Surgery, Cataracts

Alexandros Manaios

Board Certified by the European Board of Ophthalmology, Clinical Fellow of the “G. P. Georgariou” Scholarship
Specialties: Refractive Surgery, Cataracts